Buy Ditide (Benzthiazide with Triamterene) online

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DITIDE: PRESCRIBING INFORMATION

DESCRIPTION

Ditide tablets (Dyazide generic) are used as a potassium-conserving diuretic medication for the control of oedema in cardiac failure, cirrhosis of the liver or nephrotic syndrome, and in that associated with corticosteroid treatment.

The active ingredients of Ditide are Benzthiazide and Triamterene. Each tablet of Ditide (Benzthiazide and Triamterene) for oral use contains Benzthiazide 25 mg and Triamterene 50 mg.


INDICATIONS AND USAGE

Ditide is used to treat fluid retention (edema) and high blood pressure (hypertension). It contains a combination of benzthiazide and triamterene. Benzthiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention. Triamterene is a potassium-sparing diuretic that also prevents your body from absorbing too much salt and keeps your potassium levels from getting too low.


DOSAGE AND ADMINISTRATION

Ditide dosage and administration


CONTRAINDICATIONS

Ditide tablets (Benzthiazide with Triamterene) are contraindicated in patients with a hypersensitivity to Triameterene, Benzthiazide or any inactive ingredient present in this drug. Ditide is also contraindicated in the following cases: progressive renal failure, hyperkalaemia, increasing hepatic dysfunction, diabetic ketoacidosis, hypercalcaemia, and Addison's disease.

The common concomitant administration of potassium supplements, or other potassium-conserving drugs, including ACE inhibitors are also contraindicated.


ADVERSE REACTIONS / SIDE EFFECTS

Ditide side effects


WARNINGS AND PRECAUTIONS

Use Ditide (Benzthiazide, Triameterene) with caution in patients with hepatic or renal insufficiency; in those predisposed to gout, since both components can elevate uric acid levels; with hypotensive agents since and additive effect may result; in diabetic patients since thiazides can cause hyperglycaemia and glycosuria; in diabetic nephropathy due to increased risk of hyperkalaemia.

It is advisable to monitor blood urea, serum potassium levels and electrolytes periodically. This is important in the elderly, those with renal impairment and those receiving concomitant treatment with NSAID's. Triamterene and thiazides reduce excretion of lithium and may thus precipitate intoxication.

Very rare cases of SLE have been reported associated with triamterene and hydrochlorothiazide. Aggravation of pancreatisis may also occur. Combinations of folate antagonists and triamterene are not advisable during pregnancy or in patients with cirrhosis because of the increased theoretical risk of folate deficiency developing.

Ditide tablets may cause the urine to be coloured fluorescent blue. Photosensitivity has been reported quite frequently in patients with treaments containing triamterene. Patients must be advised about this side effect and to take adequate precautions.


PREGNANCY AND NURSING MOTHERS

Ditide pregnancy and nursing mothers


OVERDOSAGE

Overdose symptoms of taking Ditide tablets include symptoms of especially hyperkalaemia, electrolyte imbalance, vomiting, nausea, weakness, muscular weakness, lassitude, hypotension and cardiac arrhythmias.

The treatment of overdose consists of gastric lavage with careful monitoring of electrolytes and fluid balance. Cardiac rhythm should be monitored and appropriate measures should be taken to correct hyperkalaemia as required. There is no specific antidote for overdosage by Triameterene with Benzthiazide tablets (Ditide).

Manufactured and distributed by GlaxoSmithKline pharmaceutical company and its divisions.

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